What is acid peptic disease?
Acid peptic disease – commonly called APD – includes a number of conditions. All these conditions are the result of damage from acid and peptic activity in gastric secretions. APD occurs when the acid starts irritating the inner cells (mucosal layer) of the stomach. Acid peptic diseases mostly affect the esophagus, stomach, and duodenum.
Acid peptic diseases are caused by the excessive presence of acid and pepsin. The two main types of acid-peptic diseases are gastric and duodenal ulcers. However, they can also occur at the GJ Stoma, the lower end of the esophagus, and Meckel’s diverticulum. According to the duration and complexity of symptoms they can be acute or chronic.
What are the symptoms of the acid peptic disease?
A digestive function disorder, the acid peptic disease is characterized by dyspepsia (discomfort, heartburn, or nausea). However, the classic symptom of peptic ulcer disease, is defined as pain centered in the upper abdomen or discomfort characterised by fullness, bloating, distention, or nausea. Factors contributing to acid peptic disorder Acid peptic disorder results when the balance between the aggressive and defensive factors in the gastroduodenal mucosa is disrupted. This balance could be disrupted by factors such as H pylori infection, NSAID (Non-steroidal anti-inflammatory drug), and acid secretory abnormalities. A defect in bicarbonate production and acid neutralisation in the duodenal bulb is also a potent cause.
Factors that lead to acid peptic disorder
- Smoking
- Alcohol
NSAIDs including aspirin - Foods
- Citrus or acidic fruits
- Chocolate, caffeine, and alcohol
- Greasy, fatty, spicy, and fried foods
- Garlic, onions, and mint flavourings
- Drugs, such as aspirin and types of steroids
- Helicobacter pylori
Hyperacidity and its signs &t symptoms?
Hyperacidity, also known as acid dyspepsia, is the excessive acid secretion that causes irritation and inflammation of the internal lining of the stomach.
Signs and symptoms of hyperacidity include:
- Burning sensation in the chest and stomach
- Bloating
- Belching
- Sour eructation
- Nausea, along with occasional vomiting
- Indigestion
What are the causes of hyperacidity?
- Overeating or eating fatty/spicy foods
- Overconsumption of coffee or tea
- Irregular eating habits
- Smoking
- Emotional stress and worry
Composition
Clinical Pharmacology
Pharmacological actions of principal ingredients
Cytoprotective and ulcer-healing actions
Antioxidant action:
Tej pattar (Cinnamomum tamala) , Pudina satwa (Mentha pipereta), Jaiphal (Myristica fragrans) have antioxidant activities that protect from free radical scavenging of the gastric mucosa.
Antacid and antiflatulent actions:
Sajji kshar is an antacid used in the symptomatic treatment of hyperacidity, indigestion, and heartburn.
Ajwain (Trychyspermum ammi) is an antacid that complements the actions of other constituents with its cooling and antiflatulent properties. It treats hyperacidity.
Yashtimadhu relieves the burning pain of NUD and peptic ulcers and reduces hyperacidity by neutralizing gastric acid.
Hacid SF
For symptomatic management of Acid peptic disease (APD) Non-ulcer dyspepsia (NUD) Gastroesophageal reflux disease (GERD) Heartburn NSAID-induced gastritis
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